Antipyretics effects Infusions Ginger Rhizome (Zingiber officinale ROSCs) in rabbits (Oryctolagus cuniculus)


abstract

This study aimed to determine the effects of the rhizome extract antipyretic. This study used 12 rabbits that is 3 test group who were given infusions of ginger rhizome with a concentration of 5%, 10%, and 15% w / v, a comparison group who were given paracetamol suspension of 1%. The provision made ​​orally. Before treatment, the rabbits first didemamkan by injecting a solution of 10% sterile peptone intraperitonal. Data were analyzed with linear regression relationship of time and measured rectal temperature, then analyzed by completely randomized rancanang. The results showed that the infusion of ginger rhizome (Zingiber officinale ROSCs) with a concentration of 5-15% have antipyretic effects on rabbit and the infusion of 15% giving effect was not statistically significantly different from the effects of paracetamol 1%.

Key words: antipyretic, ginger rhizome, rabbit

 

Efek Antipiretik Infus Rimpang Jahe (zingiber officinale Rosc) pada Kelinci (Oryctolagus cuniculus) 

Abstrak 

 
Penelitian ini dimaksudkan untuk mengetahui adanya efek antipiretik ekstrak rimpang tersebut. Penelitian ini menggunakan 12 ekor kelinci yaitu 3 kelompok uji yang diberi infus rimpang jahe dengan konsentrasi 5 %, 10 %, dan 15 % b/v, satu kelompok pembanding yang diberi suspensi parasetamol 1 %. Pemberian dilakukan peroral. Sebelum perlakuan, kelinci terlebih dahulu didemamkan dengan menyuntikkan larutan pepton steril 10 % secara intraperitonal. Data dianalisis dengan regresi linier hubungan waktu dan suhu rektal terukur, kemudian dianalisis dengan rancanang acak lengkap. Hasil penelitian menunjukkan bahwa infus rimpang jahe (Zingiber officinale Rosc) dengan konsentrasi 5-15 % mempunyai efek antipiretik pada kelinci dan infus 15 % memberikan efek yang secara statistik tidak berbeda nyata dengan efek parasetamol 1 %.


Kata kunci : antipiretik, rimpang jahe, kelinci



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